I-Feline Infectious Peritonitis: Ukuqonda isifo kwiikati

I-Feline infectious peritonitis, okanye i-FIP, ihlala isesinye sezifo ezosulelayo ezinzima kakhulu abajongana nazo kwiikati. Ibangelwa yi-feline coronavirus, intsholongwane eqhelekileyo kwiikati, ngakumbi kwiindawo zokuhlala, iikati zokuzala, kunye{1}}nemizi yeekati ezininzi. Uninzi lweekati ezivezwe kwi-coronavirus ye-feline azize ziphuhlise i-FIP. Esi sifo sicingelwa ukuba senzeke xa intsholongwane itshintsha ngaphakathi kwekati eyosulelekileyo kwaye ibangele impendulo engaqhelekanga yokuzivikela komzimba, ekhokelela ekudumbeni kuwo wonke umzimba.

I-FIP inokuchaphazela amalungu amaninzi, kuquka isibindi, izintso, amehlo kunye nenkqubo ye-nervous central. Ikhosi yesifo iyahluka ukusuka kwikati ukuya kwikati, kwaye iimpawu zokuqala zihlala zingacacanga. Ikati isenokubonakala ingasebenzi kakuhle, itye kancinci, okanye iqhube umkhuhlane ongasoze uphele. Oko kwenza kube nzima ukwahlula i-FIP kwezinye izigulo ezisekwe kwiimpawu zodwa.

Iimpawu zeklinikhi kunye nokuqhubela phambili

I-FIP idla ngokuhlelwa njengengasebenziyo, okanye imanzi, okanye{0}}engasebenziyo, okanye yomile, nangona ezinye iikati zibonisa iimpawu zazo zombini.

I-FIP emanzi ibandakanya ukuqokelelana kwamanzi kwisisu okanye esifubeni. Ukudumba kwesisu, ukubhitya, ukungakucaceli ukutya, nomkhuhlane ongapheliyo zizinto eziqhelekileyo. Xa ulwelo lujikeleza emiphungeni, ukuphefumla kunokuba nzima, kwaye ikati inokonakala ngokukhawuleza.

I-FIP eyomileyo ihlala ikhula ngaphandle kokuqokelelana okucacileyo kolwelo. Endaweni yoko, izilonda ezivuthayo zinokuvela kumalungu ahlukeneyo. Ngokuxhomekeke apho ezo zilonda zenzeka khona, iikati zinokuhlakulela ukuvutha kwamehlo, utshintsho lombono, ukunyakaza okungazinzanga, okanye ezinye iingxaki ze-neurologic. Ezinye iikati zibonisa kuphela iimpawu eziqhelekileyo zokugula kwangethuba.

Umahluko phakathi kwezi fom awusoloko ucaca. Iimpawu zeklinikhi zinokutshintsha njengoko isifo siqhubela phambili, ngoko oogqirha bezilwanyana kufuneka baqwalasele umfanekiso wonke kunokuba bathembele kuphawu olulodwa.

Indima yovavanyo lwe-antibody

Uvavanyo lwe-antibody ye-FCoV lunokubonisa ukuba ikati inyusile na ukusabela komzimba kwi-feline coronavirus. Kunokuba luncedo xa uvavanya ukuvezwa okukrokrelekayo, ngakumbi kwiindawo zokuhlala, iindawo zokufuya, kunye nezinye iindawo apho iikati zihlala ngokusondeleyo.

Uvavanyo olukhawulezayo lwe-antibody luyasebenza kwiikliniki zonyango lwezilwanyana. Zilula ukwenza kwaye zibonelela ngeziphumo ngokukhawuleza, ezinokuthi zinike oogqirha bezilwanyana ulwazi oluluncedo ngexesha lovavanyo lokuqala ngaphandle kwesidingo sezixhobo zaselebhu ezintsonkothileyo. Ngokuxhomekeke kwimveliso, iziphumo zingafundwa ngokubonakalayo okanye kunye ne-analyzer ehambelanayo.

Intsingiselo yeklinikhi yesiphumo isafuna ukutolikwa ngononophelo. Isiphumo esihle se-antibody se-FCoV sithetha ukuvezwa okanye impendulo yokuzivikela kwintsholongwane, kodwa ayiqinisekisi ukuba ikati ine-FIP. Iikati ezininzi ezivezwe kwi-feline coronavirus azikhe ziphuhlise esi sifo. Isiphumo esibi kwakhona kufuneka sitolikwe ngokomxholo, kuthathelwa ingqalelo ukusebenza kovavanyo kunye nenqanaba losulelo.

Ngesi sizathu, uvavanyo lwe-antibody lusetyenziswa ngcono njengenxalenye yovavanyo olubanzi lweklinikhi. Oogqirha bezilwanyana banokuqwalasela imbali yekati, ukuhlolwa komzimba, umsebenzi wegazi, ukufunyaniswa kwemifanekiso, kunye nezinye iimvavanyo ezifanelekileyo zokuxilonga. Ukukhethwa kovavanyo olongezelelweyo kuxhomekeke kwimeko yomntu.

Ukulawula i-coronavirus ye-feline kwiindawo ezininzi{0}}zekati

I-coronavirus ye-feline isasazeka kakhulu kwi-fecal-oral route. Iitreyi zenkunkuma ekwabelwana ngazo kunye nendawo engqonge inkunkuma inganceda ukuba isasazeke, ngakumbi kwiindawo ezihlala iikati ezininzi.

Ukucoca iitreyi zenkunkuma rhoqo, ukuziqhelanisa nococeko olufanelekileyo, ukubonelela ngendawo yokuhlala eyaneleyo, kunye nokunciphisa ukuxinana kunokunceda ukunciphisa ukujikeleza kwentsholongwane. Ukubukela iikati ngenxa yomkhuhlane oqhubekayo, ukulahleka kobunzima obungachazwanga, okanye utshintsho lokuziphatha lunokunceda ukuchonga izilwanyana ezifuna ukuhlolwa kwezilwanyana.

Usasazo lwe-FCoV kunye nophuhliso lwe-FIP lunxulumene kodwa imiba eyahlukileyo. I-coronavirus ye-feline inokusasazeka phakathi kweekati, ngelixa i-FIP idityaniswa ngokubanzi notshintsho kwintsholongwane ngaphakathi kwesilwanyana esinye. Ukunciphisa ukujikeleza kwentsholongwane ngoko ke kubalulekile, kodwa ayikwazi ukususa yonke ingozi ye-FIP.

I-FIP ihlala isisifo esintsonkothileyo esineempawu zeklinikhi eziguquguqukayo kwaye akukho vavanyo olunye oluphendula yonke imibuzo yoxilongo. Ukuqonda indlela esikhula ngayo isifo kunye nokusetyenziswa kovavanyo lwe-antibody ngenjongo yaso efanelekileyo kunganceda oogqirha bezilwanyana batolike iziphumo ngokuchanekileyo kwaye benze izigqibo ezingcono-ezinolwazi.